Carla MONTECINOS - Admise au titre de docteur

cjmontec@gmail.com

Doctorat Neurosciences

Thèse soutenue le 22 novembre 2018 - Université de Bordeaux

Ecole doctorale : Sciences de la Vie et de la Santé

Sujet : Stabilisation Des Récepteurs AMPA Médiée par la Signalisation Wnt Non-canonique Protège Contre Synaptotoxicité des Oligomères Aβ42

Mots-clés de la thèse : récepteur AMPA,Abeta,Wnt5a,

Direction de thèse : Daniel CHOQUET

Co-direction de thèse : Nibaldo INESTROSA

Cotutelle Pontificia Universidad Católica de Chile CHILI
Descriptif : Doctorate under international joint supervision leading to the award of a double degree

Unité de recherche : Institut Interdisciplinaire de Neurosciences UMR 5297 - BORDEAUX
Intitulé de l'équipe : Dynamique de l'organisation et des fonctions synaptiques

Master - Master

obtenu en septembre 2014 - Pontificia Universidad Católica de Chile
Option : Biological Sciences

Production scientifique

- Carolina A. Oliva Gutiérrez, Carla Montecinos-Oliva, Nibaldo C. Inestrosa 2018. Wnt in the Central Nervous System: New Insights in Health and Disease. Progress in Molecular Biology and Translational Science, 153; 81-130. ,
- Carla Montecinos-Oliva, Daniel Choquet, Nibaldo C. Inestrosa. 2017. AMPA receptor stabilization mediated by non-canonical Wnt signaling protects synapses against Aβ1-42 oligomers synaptotoxicity Society for Neuroscience Annual Meeting , 1,
- Carla Montecinos-Oliva, Daniel Choquet, Nibaldo C. Inestrosa. 2017. Wnt5a stabilizes AMPA receptors, causing neuroprotection against Aβ oligomers XIII Annual Meeting of Neuroscience Society of Chile , 1,
- Carla Montecinos-Oliva, Daniel Choquet, Nibaldo C. Inestrosa. 2016. The Wnt5a ligand favors immobilization of AMPA receptors in hippocampal neurons 7th EMCCS-FENS Satellite and 1st EBBS-EMCCS Joint Meeting , 1,
- Carla Montecinos-Oliva, Daniel Choquet, Nibaldo C. Inestrosa 2016. The Wnt5a ligand favors immobilization of AMPA receptors in hippocampal neurons 10th FENS Forum of Neuroscience , 1,
- Cisternas P, Salazar P, Serrano FG, Montecinos-Oliva C, Arredondo SB, Varela-Nallar L, Barja S, Vio CP, Gomez-Pinilla F, Inestrosa NC 2015. Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance. Biochimca et Biophysica Acta, 1852(11):2379-90,
- Cheril Tapia-Rojas, Carolina B. Lindsay, Carla Montecinos-Oliva, Macarena S. Arrazola, Rocio M. Retamales, Daniel Bunout, Sandra Hirsch and Ni baldo C. Inestrosa 2015. Is L-methionine a trigger factor of Alzheimer's like-neurodegeneration? Changes in Abeta oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice. Molecular Neurodegeneration , 10(1):62,
- Carla Montecinos-Oliva, Cheril Tapia-Rojas, Patricia V. Burgos and Nibaldo C. Inestrosa 2015. New Discoveries on the Hyperforin Derivative, Tetrahydrohyperforin: Closer to and Alzheimer’s Disease Treatment? Nova Publishers, 1-30,
- Carla Montecinos-Oliva, Andreas Schüller, Nibaldo C. Inestrosa 2015. Tetrahydrohyperforin - a neuroprotective modified natural compound against Alzheimer's disease Neural Regeneration Research, 10 (4):552-554,
- Codocedo JF, Montecinos-Oliva C and Inestrosa NC 2015. Wnt-related SynGAP1 is a neuroprotective factor of glutamatergic synapses against Aβ oligomers Frontiers in Cellular Neuroscience, 9 (227),
- Parodi J, Montecinos-Oliva C, Varas R, Alfaro IE, Serrano FG, Varas-Godoy M, Muñoz FJ, Cerpa W, Godoy JA, Inestrosa NC 2015. Wnt5a inhibits K+ currents in hippocampal synapses through nitric oxide production. Mol Cellular Neuroscience , 24; 68:314-322. ,
- Carla Montecinos-Oliva, Andreas Schüller, Jorge Parodi, Francisco Melo, Nibaldo C. Inestrosa 2014. Effect of Tetrahydrohyperforin on Hippocampal Mice Slices: Neuroprotection, LTP and TRPC channels Current Medicinal Chemistry, 21 (30):3494-3506,
- Carla Montecinos-Oliva, Anne-Sophie Hafner, Daniel Choquet, Nibaldo C. Inestrosa 2014. Impact of the Wnt non-canonical signaling pathway on AMPA receptors synaptic enrichment 9th FENS Forum of Neuroscience , 1,
- Cheril Tapia-Rojas, Carla Montecinos-Oliva, Carolina B. Lindsay, Sandra Hirsch, Nibaldo C. Inestrosa 2013. Chronic treatment of wild-type mice with high doses of methionine induces neurodegeneration XXVII Annual Meeting of Cellular Biology Society of Chile , 1,
- Carla Montecinos-Oliva & Nibaldo C. Inestrosa. 2013. Non-canonical Wnt signaling increases AMPA receptor clusters in hippocampal neurons XXVII Annual Meeting of Cellular Biology Society of Chile , 1,
- Andreas Schuller, Carla Montecinos-Oliva, Jorge Parodi, Nibaldo C. Inestrosa. 2012. In silico analysis of tetrahydrohyperforin suggests a potential pharmacophore for the activation of TRPC6 channels XXXV Annual Meeting of Biochemistry and Molecular Biology , 1,
- Carla Montecinos-Oliva, Rodrigo Varas, Nibaldo C. Inestrosa 2012. Nitric oxide is a key novel factor in Wnt-5a signaling in synapses XXVI Annual Meeting of Cellular Biology Society of Chile , 1,
- Nibaldo C. Inestrosa, Carla Montecinos-Oliva, Marco Fuenzalida 2012. Wnt signaling: role in Alzheimer disease and Schizophrenia Journal of Neuroimmune Pharmacology, 7 (4):788-807.,
- Carla Montecinos-Oliva, Felipe G. Serrano, Cheril Tapia-Rojas, Jorge Parodi, Nibaldo C. Inestrosa 2011. Tetrahydrohyperforin prevents cognitive failure in double transgenic (APPswe/PSEN1ΔE9) mice model of Alzheimer´s Disease with activation of TRPC6 as a possible mechanism VII Annual Meeting of Neuroscience Society of Chile, 1,

Dernière mise à jour le 6 décembre 2018